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XPC (gene)
Xeroderma pigmentosum, complementation group C, also known as XPC, is a protein which in humans is encoded by the ''XPC'' gene. XPC is involved in the recognition of bulky DNA adducts in nucleotide excision repair.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7508 )〕 It is located on chromosome 3. == Function ==
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「XPC (gene)」の詳細全文を読む
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